Blog Details

Drug License in Karnataka – Step-by-Step Process, CDSCO Forms, Renewal & Online Application (2026)
Drug License

Tue, Jan 06 2026

Raju Karn

Drug License in Karnataka – Step-by-Step Process, CDSCO Forms, Renewal & Online Application (2026)

Starting or running a pharmaceutical business in Karnataka without a valid drug license is not just risky-it can shut down your operations overnight. Whether you are a wholesaler in Bengaluru, a retailer in Mysuru, or a manufacturer supplying across India, drug license registration is legally mandatory under the Drugs and Cosmetics Act. Yet, many businesses still struggle with drug license verification, Form 20 and 21 applications, CDSCO login issues, and renewal timelines.

If you are searching for a clear, step-by-step guide for drug license in Karnataka (2026)-covering CDSCO online, ONDLS CDSCO, CDSCO Sugam portal, documents, fees, validity, and compliance-this guide will help you make the right decisions from day one.

PSR Compliance assists businesses across Karnataka and India with drug license registration, renewal, and CDSCO approvals, ensuring your business remains compliant and growth-ready.

What Is a Drug License?

A drug license is a legal authorization issued by the State Drug Control Department or CDSCO (Central Drugs Standard Control Organization) that allows a business to:

  • Manufacture medicines
  • Sell drugs wholesale or retail
  • Distribute pharmaceutical products
  • Import or export regulated drugs

Without a valid license, any activity involving drugs is considered illegal under Indian law.

CDSCO Full Form & Role

CDSCO full form: Central Drugs Standard Control Organization

CDSCO is India’s national regulatory authority responsible for:

➜ Approval of new drugs and medical devices

➜ Regulation of clinical trials

➜ Import/export permissions

➜ Oversight of drug manufacturing and quality

Businesses in Karnataka must comply with both State Drug Control Department regulations and CDSCO guidelines.

Types of Drug Licenses in Karnataka

Depending on your business model, you may need one or more of the following:

Retail Drug License

For medical stores and pharmacies selling directly to consumers.

Wholesale Drug License

For distributors, stockists, and suppliers selling to retailers, hospitals, or clinics.

● Manufacturing Drug License

For companies producing medicines or pharmaceutical formulations.

Loan License

For businesses manufacturing drugs using another company’s facilities.

● Import / Export Drug License (CDSCO Online)

For companies importing or exporting pharmaceutical products.

Key Drug License Forms – Form 20 & 21

Form 20 Drug License

  • Issued for retail sale of drugs
  • Mandatory for pharmacies and chemists

Form 21 Drug License

  • Issued for wholesale distribution
  • Required for distributors and suppliers

Both forms are issued by the State Drug Control Department in Karnataka after verification of premises, staff qualifications, and compliance standards.

Why Drug License Is Important

Holding a valid drug license is not just a legal formality-it directly impacts business credibility and growth.

Advantages of Drug License Registration

– Legal authorization to operate

– Eligibility to supply hospitals, clinics, and government tenders

– Business expansion across states

– Easy drug license verification by partners and authorities

– Builds trust with customers and distributors

– Required for CDSCO approved drug distribution

Who Needs a Drug License in Karnataka?

You must apply for a drug license if you are:

➝ A medical store owner

➝ A pharmaceutical wholesaler or distributor

➝ A drug manufacturer

➝ A hospital or clinic with in-house pharmacy

➝ An online pharmacy

➝ An importer or exporter of medicines

Documents Required for Drug License in Karnataka

Business Documents

• Certificate of Incorporation / Partnership Deed / Proprietorship Proof

• PAN Card

• GST Registration

• Address proof of business premises

Premises Documents

• Rental Agreement or Ownership Proof

• Site plan / layout of shop or warehouse

• Storage facility details (refrigeration if required)

Staff & Technical Documents

• Qualification certificates of registered pharmacist / competent person

• Appointment letter

• Experience certificates (for wholesale)

Compliance Documents

• Affidavit of compliance

• Declaration of drug categories

• Application forms (Form 20 / Form 21 / Manufacturing forms)

Step-by-Step Process for Drug License in Karnataka (2026)

Step 1: Determine the License Type

Identify whether you need retail, wholesale, manufacturing, or CDSCO import/export license.

Step 2: Prepare Documents

Compile all business, premises, and technical documents.

Step 3: Online Application

Apply through the state drug control portal or CDSCO online system where applicable.

Step 4: Site Inspection

Drug inspectors verify:

  • Storage conditions
  • Premises size
  • Presence of qualified staff
  • Safety and hygiene standards

Step 5: Approval & Issuance

After successful inspection, your drug license certificate is issued.

CDSCO Online, ONDLS & Sugam Portal

CDSCO Online

Used for approvals related to imports, exports, medical devices, and new drugs.

ONDLS CDSCO (Online National Drug Licensing System)

A centralized digital platform for application, tracking, and compliance.

CDSCO Sugam Portal

For:

  • Import/export applications
  • Clinical trial permissions
  • Registration of drugs and devices
  • Access to CDSCO approved drug lists

You can track applications using:

➤ CDSCO login

➤ CDSCO MD online system

➤ CDSCO Sugam portal dashboard

Drug License Renewal in Karnataka

A drug license is not permanent-it must be renewed before expiry.

Renewal Process

▪ Update documents

▪ Submit renewal application

▪ Pay government fees

▪ Undergo re-inspection if required

Why Renewal Is Critical

▪ Avoid penalties and cancellation

▪ Prevent disruption in supply chain

▪ Maintain eligibility for tenders and partnerships

PSR Compliance handles drug license renewal with complete follow-ups and documentation support.

Fees, Timeline & Validity

Government Fees (Approx.)

Retail / Wholesale License: ₹3,000 – ₹10,000

Manufacturing License: ₹10,000 – ₹50,000+
(Fees may vary based on category and state rules)

Timeline

Application Processing: 15–30 working days

Inspection & Approval: 7–15 days

Validity

Typically 5 years

Renewal required before expiry

Real Business Experience from Karnataka

In 2025, Mr. Suresh Reddy, who operates a pharmaceutical distribution firm in Yelahanka, Bengaluru, approached PSR Compliance after one of his hospital clients asked for drug license verification and found that his Form 21 license was close to expiry. Due to a missed renewal deadline, his distributor registration was temporarily blocked, and two large supply orders were put on hold.

Our team immediately reviewed his compliance status, prepared renewal documentation, updated records on the ONDLS CDSCO system, and coordinated with the Drug Control Department. We also ensured his business details were properly reflected on the CDSCO Sugam portal. Within a short period, his drug license renewal was approved, and hospital contracts were reinstated. Today, his operations run smoothly with proper compliance and digital verification in place.

How PSR Compliance Helps with Drug License in Karnataka

PSR Compliance provides end-to-end drug licensing services for businesses across Karnataka and India.

Our Services Include:

☑ Drug license registration (Retail, Wholesale, Manufacturing)

☑ Form 20 and 21 application handling

☑ CDSCO online filing & ONDLS management

☑ Drug license verification assistance

☑ Renewal, modification & compliance support

☑ Import/export drug license & CDSCO approvals

We handle everything-from documentation to inspections-so you can focus on growing your pharmaceutical business.

Frequently Asked Questions (FAQs)

1️⃣ What is a drug license?

A drug license is a legal authorization to manufacture, sell, or distribute pharmaceutical products in India.

2️⃣ What is the CDSCO full form?

CDSCO stands for Central Drugs Standard Control Organization, India’s national drug regulatory authority.

3️⃣ What are Form 20 and 21 drug licenses?

Form 20 is for retail sale, while Form 21 is for wholesale distribution of drugs.

4️⃣ Is drug licesne mandatory in Karnataka?

Yes. Operating without a valid drug license is illegal and punishable under the Drugs and Cosmetics Act.

5️⃣ How can I verify a drug license?

Drug license verification can be done through the state drug control portal or CDSCO platforms using the license number.

6️⃣ What is CDSCO Sugam portal?

It is an online system for drug approvals, imports, exports, and regulatory submissions.

7️⃣ How long does drug license approval take?

Typically 3–6 weeks depending on inspection and document verification.

8️⃣ What is the validity of a drug license?

Usually valid for 5 years, after which renewal is required.

9️⃣ Can I apply for drug license online?

Yes. Applications can be submitted through state portals and CDSCO online / ONDLS CDSCO systems.

🔟 How can PSR Compliance help?

PSR Compliance provides complete support for registration, renewal, verification, and CDSCO compliance across Karnataka and India.

Contact Us

Start a New Case? Contact
Our Experts

Just send us your questions or concerns by starting a new case &
we will give you the help you need. Start Here...

Have a Question?

070658 83416
  • Monday - Friday:
  • 9.00 - 6.00
  • Sunday & Public Holidays (Closed)
Request a Call Back