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Indian businessman in formal attire standing in a pharmaceutical warehouse, holding drug license documents, with framed wholesale drug license certificates on the wall – representing the process of starting a medicine wholesale business in India.
Medicine Wholesale Business

Fri, Jul 25 2025

Shubham Bansal

Start Your Medicine Wholesale Business in India (2025 Guide)

India’s pharmaceutical industry is booming, and entering the medicine wholesale business can be a highly profitable opportunity—if done right. However, it requires proper licensing, legal compliance, and a solid understanding of how the wholesale supply chain works. This guide will walk you through every detail of starting a wholesale medicine business in India—from licensing to growth strategies.

Why Start a Wholesale Medicine Business in India?

High Demand for Affordable Medicines

India has one of the world’s largest populations needing affordable and quality medicines. Hospitals, clinics, and retail pharmacies rely heavily on wholesalers for consistent supplies.

Pandemic-Driven Health Awareness

The COVID-19 pandemic has increased health awareness, driving demand for essential medicines, vaccines, and health supplements—making this business more future-proof than ever.

Opportunities in Tier-2 and Tier-3 Cities

Many remote and semi-urban areas are underserved. Wholesalers can create a strong distribution network in these regions and build a loyal customer base.

Market Potential and Growth Opportunities

Indian Pharmaceutical Industry Overview

India is the third-largest pharmaceutical producer by volume globally. The industry is expected to reach USD 130 billion by 2030, presenting ample room for new wholesale businesses.

Export Potential for Generic Medicines

Medicine wholesalers can also venture into exports, especially for generic medicines, which are highly demanded in African, Asian, and Latin American countries.

Government Support & PLI Scheme

Government initiatives like the Production Linked Incentive (PLI) scheme are pushing pharmaceutical growth, creating a favorable environment for wholesalers.

Wholesale vs. Retail Drug License – Key Differences

Purpose and Scope of Each License

  • Retail Drug License: For selling directly to consumers.

  • Wholesale Drug License: For selling medicines in bulk to retailers, hospitals, and institutions.

Regulatory Authorities Involved

Both are governed by the Drugs and Cosmetics Act, 1940, but wholesale licenses have more rigorous conditions regarding distribution and storage.

Benefits of Choosing Wholesale Over Retail

  • Higher profit margins

  • Larger business scale

  • Easier to work with bulk suppliers and manufacturers

Types of Drug Licenses Required for Wholesale

Drug License Form 20B and 21B

  • Form 20B: Required for dealing in general drugs.

  • Form 21B: Required if dealing with Schedule C & C1 drugs (like vaccines or injectables).

Additional Licenses for Specific Categories

  • Narcotics License: If dealing with psychotropic substances

  • FSSAI License: If you plan to sell dietary supplements or nutraceuticals

Central vs. State Licensing Authorities

Licensing is regulated by the State Drug Control Department, but central approval is required for narcotic or controlled substances.

Step-by-Step Process to Get a Wholesale Drug License

Step 1: Register Your Business

Choose the right entity:

  • Proprietorship

  • Partnership

  • LLP or Private Limited Company (preferred for scalability)

Step 2: Prepare Premises and Storage Facility

  • Minimum 10 square meters of space

  • Air conditioning and refrigeration (for temperature-sensitive drugs)

  • Proper labeling and racking systems

Step 3: Appoint a Registered Pharmacist or Competent Person

You must appoint someone with:

  • B.Pharm/D.Pharm degree

  • Minimum 1–4 years of experience in drug sales (varies by state)

Step 4: Submit Application to Drug Control Department

Apply through your state’s drug control office or online portal, along with required documents and fees.

Step 5: Inspection and Final Approval

Authorities will inspect the premises and storage facilities. Once approved, your license will be issued within 30–60 days.

Documents Required for Wholesale Drug License

  • Business registration documents

  • Rental agreement/ownership proof of premises

  • Pharmacist’s qualification and registration certificate

  • Identity & address proof of all partners/directors

  • Site layout and storage details

  • Affidavit declaring compliance with the Drugs Act

Compliance & Legal Requirements You Must Follow

Record-Keeping for Purchase and Sales

Maintain detailed records of every sale, return, and batch number as per Schedule H/H1 requirements.

Maintain Proper Storage Conditions

Temperature-sensitive drugs must be stored in refrigerators or cold storage units. Daily temperature logs are often required.

Timely License Renewal

The wholesale license is usually valid for 5 years. Make sure to renew before expiry to avoid penalties.

Avoid Blacklisted or Unlicensed Suppliers

Procure medicines only from licensed manufacturers and avoid counterfeit or misbranded drugs at all costs.

Tips to Grow and Scale Your Wholesale Medicine Business

Build Network with Retailers & Clinics

Offer credit periods, discounts, and efficient delivery to build long-term relationships with clients.

Invest in Inventory Management Software

Use technology to track stock levels, expiry dates, batch numbers, and automate billing.

Ensure Timely Delivery and Distribution

Quick and efficient logistics is a competitive edge. Tie up with local delivery partners or invest in your own transport system.

Stay Updated on Drug Price Control Orders (DPCO)

Keep an eye on pricing regulations by NPPA to avoid legal issues while pricing your medicines.

FAQs about Wholesale Drug License in India

Can I get a drug license without a pharmacy degree?

You can apply if you appoint a qualified person (Registered Pharmacist or Competent Person) for your business.

How much investment is needed to start a medicine wholesale business?

Typically ₹5–10 lakhs is required initially including premises, inventory, staffing, and licensing.

Is GST registration mandatory for a wholesale medicine business?

Yes, GST registration is mandatory for any business involved in the sale of goods in India.

Final Thoughts

Starting a medicine wholesale business in India can be highly rewarding if you follow the right legal procedures and build strong industry relationships. From obtaining licenses like Form 20B and 21B to ensuring legal compliance and leveraging growth strategies—each step matters.

👉 Need expert help with Wholesale Drug License or Compliance? Visit: https://www.psrcompliance.com

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